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Small clinical trials have demonstrated mixed effects on the lipid profile in humans. Royal jelly administered at 10 g/day for 14 days increased serum high-density lipid (HDL) levels in elderly participants, while a trend toward improved low-density lipid (LDL) levels was seen with no effect on serum triglycerides.  

 In another trial, 6 g/day for 4 weeks resulted in decreased serum total cholesterol and LDL, but had no effect on HDL or triglycerides.