Royal jelly may cause allergic reactions in humans ranging from hives, to more severe and even life threatening symptoms.

Side Effects:
Signs and symptoms : What to do?
Life-threatening anaphylaxis may follow injections:

Symptoms include : 

Immediate severe itching

Paleness 

Low blood pressure 

Loss of consciousness 

Coma.

What to do.

Call for help. 

Don’t leave victim.

Begin CPR (cardio pulmonary resuscitation), mouth-to-mouth breathing and external cardiac massage. Have someone dial emergency. Don’t stop CPR until help arrives.

The incidence of allergic side effects in people that consume royal jelly is unknown. However, it has been suggested that the risk of having an allergy to royal jelly is higher in people who already have known allergies.